Total CLP36 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3438C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- PDLIM1
- Human Gene Id:
- 9124
- Human Swiss Prot No:
- O00151
- Mouse Swiss Prot No:
- O70400
- Rat Swiss Prot No:
- P52944
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)
- Detection Method:
- Colorimetric
- Background:
- function:Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Associates with the actin stress fibers.,subunit:Interacts with alpha-actinins 1, 2 and 4.,tissue specificity:Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.,
- Function:
- response to hypoxia, response to oxidative stress, regulation of transcription, response to oxygen levels,
- Subcellular Location:
- Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Associates with actin stress fibers. .
- Expression:
- Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.
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