Total NUB1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3409C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • NUB1
    • Human Swiss Prot No:
    • Q9Y5A7
    • Mouse Swiss Prot No:
    • P54729
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • NEDD8 ultimate buster 1 (Negative regulator of ubiquitin-like proteins 1) (Renal carcinoma antigen NY-REN-18)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8 and its conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.,induction:By beta and gamma interferons.,similarity:Contains 3 UBA domains.,subcellular location:Predominantly nuclear.,subunit:Directly interacts with NEDD8 and PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome. Isoform 1 binds to NEDD8 more efficiently than isoform 2. Interacts with AIPL1.,tissue specificity:Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.,
    • Subcellular Location:
    • Nucleus . Predominantly nuclear.
    • Expression:
    • Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.