Total SAE1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3401C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • SAE1
    • Human Swiss Prot No：
    • Q9UBE0
    • Mouse Swiss Prot No：
    • Q9R1T2
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • SUMO-activating enzyme subunit 1 (Ubiquitin-like 1-activating enzyme E1A)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:The dimeric enzyme acts as a E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.,pathway:Protein modification; protein sumoylation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ubiquitin-activating E1 family.,subunit:Heterodimer of SAE1 and SAE2. The complex binds SUMO proteins via SAE2.,tissue specificity:Expression level increases during S phase and drops in G2 phase (at protein level).,
    • Function：
    • proteolysis, macromolecule catabolic process, protein ubiquitination, modification-dependent protein catabolic process,protein catabolic process, protein modification by small protein conjugation, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process, proteolysis involved in cellular protein catabolic process, protein modification by small protein conjugation or removal,
    • Subcellular Location：
    • Nucleus .
    • Expression：
    • Expression level increases during S phase and drops in G2 phase (at protein level).

    Attributes

    • Code：
    • KA3401C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-02
    Order

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