• Gene Name：
• TGFB2

• Human Gene Id：
• 7042

• Human Swiss Prot No：
• P61812

• Mouse Swiss Prot No：
• P27090

• Rat Swiss Prot No：
• Q07257

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• Transforming growth factor beta-2 (TGF-beta-2) (BSC-1 cell growth inhibitor) (Cetermin) (Glioblastoma-derived T-cell suppressor factor) (G-TSF) (Polyergin)

• Detection Method：
• Colorimetric

• Background：
• disease:A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly [MIM:604229]. Translocation t(1;7)(q41;p21) with HDAC9. Peters anomaly consists of a central corneal leukoma, absence of the posterior corneal stroma and Descemet membrane, and a variable degree of iris and lenticular attachments to the central aspect of the posterior cornea.,function:TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.,online information:TGF beta-2 entry,similarity:Belongs to the TGF-beta family.,subunit:Homodimer; disulfide-linked.,

• Function：
• protein import into nucleus, translocation, cell morphogenesis, cell morphogenesis involved in differentiation,angiogenesis, regulation of cell growth, blood vessel development, eye development, response to hypoxia, regulation of cytokine production, epithelial to mesenchymal transition, hair follicle development, vasculature development,immune system development, negative regulation of immune system process, positive regulation of immune system process, reproductive developmental process, heart morphogenesis, protein amino acid phosphorylation, cellular amino acid derivative metabolic process, biogenic amine metabolic process, catecholamine metabolic process, protein targeting, protein import into nucleus, phosphorus metabolic process, phosphate metabolic process, intracellular protein transport, nucleocytoplasmic transport, cell motion, chemotaxis, cell cycle, cell cycle arrest, cell s

• Subcellular Location：
• [Latency-associated peptide]: Secreted, extracellular space, extracellular matrix .; [Transforming growth factor beta-2]: Secreted .

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