Total Oct-2 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3342C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • POU2F2
    • Human Gene Id：
    • 5452
    • Human Swiss Prot No：
    • P09086
    • Mouse Swiss Prot No：
    • Q00196
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)
    • Detection Method：
    • Colorimetric
    • Background：
    • function:Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR and PGR.,tissue specificity:Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line Molt-4, but not in the T-cell line BW 5147.,
    • Function：
    • transcription, transcription, DNA-dependent, regulation of transcription, DNA-dependent, transcription from RNA polymerase II promoter, immune response, humoral immune response, RNA biosynthetic process, regulation of transcription, regulation of RNA metabolic process,
    • Subcellular Location：
    • Cytoplasm . Nucleus.
    • Expression：
    • Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.

    Attributes

    • Code：
    • KA3342C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-10
    Order

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