Total MMP-3 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3332C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • MMP3
    • Human Gene Id:
    • 4314
    • Human Swiss Prot No:
    • P08254
    • Mouse Swiss Prot No:
    • P28862
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Stromelysin-1 (SL-1) (EC 3.4.24.17) (Matrix metalloproteinase-3) (MMP-3) (Transin-1)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:Preferential cleavage where P1', P2' and P3' are hydrophobic residues.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 4 calcium ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
    • Function:
    • response to acid, proteolysis, response to endogenous stimulus, response to organic substance, response to organic nitrogen, response to amine stimulus, collagen catabolic process, collagen metabolic process, response to cytokine stimulus, response to amino acid stimulus, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
    • Subcellular Location:
    • Secreted, extracellular space, extracellular matrix .