Total MMP-10 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3323C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • MMP10
    • Human Gene Id:
    • 4319
    • Human Swiss Prot No:
    • P09238
    • Mouse Swiss Prot No:
    • O55123
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:Similar to stromelysin 1, but action on collagen types III, IV and V is weak.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
    • Function:
    • proteolysis, collagen catabolic process, collagen metabolic process, multicellular organismal metabolic process,multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
    • Subcellular Location:
    • Secreted, extracellular space, extracellular matrix .