Total MMP-10 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3323C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- MMP10
- Human Gene Id:
- 4319
- Human Swiss Prot No:
- P09238
- Mouse Swiss Prot No:
- O55123
- Rat Swiss Prot No:
- P07152
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:Similar to stromelysin 1, but action on collagen types III, IV and V is weak.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
- Function:
- proteolysis, collagen catabolic process, collagen metabolic process, multicellular organismal metabolic process,multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix .
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