Total mGluR-4 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3274C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- GRM4
- Human Gene Id:
- 2914
- Human Swiss Prot No:
- Q14833
- Mouse Swiss Prot No:
- Q68EF4
- Rat Swiss Prot No:
- P31423
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Metabotropic glutamate receptor 4 (mGluR4)
- Detection Method:
- Colorimetric
- Background:
- function:Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity.,similarity:Belongs to the G-protein coupled receptor 3 family.,subunit:Interacts with PICK1.,tissue specificity:Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.,
- Function:
- MAPKKK cascade, activation of MAPK activity, regulation of neurotransmitter levels, generation of a signal involved in cell-cell signaling, regulation of nucleotide metabolic process, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, neurotransmitter transport, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, G-protein signaling, coupled to cyclic nucleotide second messenger, G-protein signaling, coupled to cAMP nucleotide second messenger, inhibition of adenylate cyclase activity by G-protein signaling, negative regulation of adenylate cyclase activity, inhibition of adenylate cyclase activity by metabotropic glutamate receptor signaling pathway, glutamate signaling pathway, metabotropic glutamate receptor signaling pathway, intracellular signaling cascade, protein kinase cascade, cell-ce
- Subcellular Location:
- Cell membrane ; Multi-pass membrane protein .
- Expression:
- Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.
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