• Gene Name：
• MCM3AP

• Human Gene Id：
• 8888

• Human Swiss Prot No：
• O60318

• Mouse Swiss Prot No：
• Q9WUU9

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• 80 kDa MCM3-associated protein (Protein GANP)

• Detection Method：
• Colorimetric

• Background：
• function:May be involved in the nuclear localization pathway of MCM3.,similarity:Belongs to the SAC3 family.,subunit:Interacts with MCM3.,

• Function：
• DNA metabolic process, DNA replication, protein targeting, protein import into nucleus, intracellular protein transport,nucleocytoplasmic transport, protein localization, protein transport, protein import, protein localization in organelle,protein localization in nucleus, cellular protein localization, establishment of protein localization, intracellular transport,nuclear transport, nuclear import, cellular macromolecule localization,

• Subcellular Location：
• [Isoform GANP]: Nucleus envelope . Nucleus, nuclear pore complex . Nucleus, nucleoplasm . Chromosome . Predominantly located at the nuclear envelope, facing the nucleus interior (PubMed:20005110, PubMed:21195085, PubMed:23591820). Localization at the nuclear pore complex requires NUP153, TPR and ALYREF/ALY (PubMed:23591820, PubMed:22307388). Also found associated with chromatin (PubMed:23652018). In B-cells, targeted to the immunoglobulin variable region genes (PubMed:23652018). .; [Isoform MCM3AP]: Cytoplasm . Nucleus . Translocates into the nucleus in the presence of MCM3 (PubMed:12226073). Associates with chromatin possibly through interaction with MCM3 (PubMed:12226073). .

• Expression：
• Widely expressed (PubMed:11024281). Up-regulated in germinal center B-cells in tonsils (at protein level) (PubMed:11024281).

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