• Gene Name：
• GFRA1

• Human Gene Id：
• 2674

• Human Swiss Prot No：
• P56159

• Mouse Swiss Prot No：
• P97785

• Rat Swiss Prot No：
• Q62997

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• GDNF family receptor alpha-1 (GDNF receptor alpha-1) (GDNFR-alpha-1) (GFR-alpha-1) (RET ligand 1) (TGF-beta-related neurotrophic factor receptor 1)

• Detection Method：
• Colorimetric

• Background：
• function:Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.,similarity:Belongs to the GDNFR family.,subunit:2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.,

• Function：
• cell surface receptor linked signal transduction,

• Subcellular Location：
• Cell membrane ; Lipid-anchor, GPI-anchor . Golgi apparatus, trans-Golgi network . Endosome . Endosome, multivesicular body . Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and multivesicular bodies. .

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