Total ERCC1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3251C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • ERCC1
    • Human Gene Id：
    • 2067
    • Human Swiss Prot No：
    • P07992
    • Mouse Swiss Prot No：
    • P07903
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • DNA excision repair protein ERCC-1
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Defects in ERCC1 are the cause of cerebro-oculo-facio-skeletal syndrome type 4 (COFS4) [MIM:610758]. COFS is a degenerative autosomal recessive disorder of prenatal onset affecting the brain, eye and spinal cord. After birth, it leads to brain atrophy, hypoplasia of the corpus callosum, hypotonia, cataracts, microcornea, optic atrophy, progressive joint contractures and growth failure. Facial dysmorphism is a constant feature. Abnormalities of the skull, eyes, limbs, heart and kidney also occur.,function:Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.,similarity:Belongs to the ERCC1/RAD10/SWI10 family.,subunit:Heterodimer composed of ERCC1 and XPF/ERRC4.,
    • Function：
    • nucleotide-excision repair, DNA damage removal, pyrimidine dimer repair by nucleotide-excision repair, DNA catabolic process, endonucleolytic, replicative cell aging, cell activation, somatic diversification of immune receptors, somatic recombination of immunoglobulin genes during immune response, somatic diversification of immunoglobulins during immune response, adaptive immune response, immune effector process, immunoglobulin production, immunoglobulin production during immune response, production of molecular mediator of immune response, leukocyte mediated immunity, lymphocyte mediated immunity, adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains, immune system development, somatic diversification of immune receptors via germline recombination within a single locus, reproductive developmental process, DNA metabolic
    • Subcellular Location：
    • [Isoform 1]: Nucleus .; [Isoform 2]: Cytoplasm . Nucleus .; [Isoform 3]: Nucleus .; [Isoform 4]: Nucleus .

    Attributes

    • Code：
    • KA3251C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-08-03
    Order

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