Total Claudin-3 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3217C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • CLDN3
    • Human Gene Id:
    • 1365
    • Human Swiss Prot No:
    • O15551
    • Mouse Swiss Prot No:
    • Q9Z0G9
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:Haploinsufficiency of CLDN3 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
    • Function:
    • response to hypoxia, cell adhesion, cell-cell adhesion, calcium-independent cell-cell adhesion, biological adhesion,response to oxygen levels,
    • Subcellular Location:
    • Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .