Total Claudin-4 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3215C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • CLDN4
    • Human Gene Id:
    • 1364
    • Human Swiss Prot No:
    • O14493
    • Mouse Swiss Prot No:
    • O35054
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (Williams-Beuren syndrome chromosomal region 8 protein)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:Haploinsufficiency of CLDN4 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space.,similarity:Belongs to the claudin family.,subunit:Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
    • Function:
    • cell adhesion, pathogenesis, cell-cell adhesion, calcium-independent cell-cell adhesion, biological adhesion,
    • Subcellular Location:
    • Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .