Total Catenin-α E/N Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA3213C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • CTNNA1/CTNNA2
    • Storage Stability：
    • 2-8°C/6 months
    • Detection Method：
    • Colorimetric
    • Background：
    • disease:Abnormalities of alpha-catenin are involved in the process of cancer invasion and metastasis.,function:Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. May play a crucial role in cell differentiation.,PTM:Sumoylated.,similarity:Belongs to the vinculin/alpha-catenin family.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,subunit:Binds MLLT4 and F-actin (By similarity). Interacts directly with PSEN1 and CTNNB1 to form part of the PSEN1/cadherin/catenin adhesion complex. Interacts with ARHGAP21 and with JUB.,tissue specificity:Expressed ubiquitously in normal tissues.,
    • Function：
    • cell-cell junction assembly, cell adhesion, biological adhesion, cell junction assembly, cell junction organization, apical junction assembly, cell-cell junction organization,
    • Subcellular Location：
    • [Isoform 1]: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.; [Isoform 3]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .
    • Expression：
    • Expressed ubiquitously in normal tissues.

    Attributes

    • Code：
    • KA3213C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-11
    Order

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