Total Gab 1 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3112C
- Applications:ELISA
- Reactivity:Human;Mouse
- Gene Name:
- GAB1
- Human Gene Id:
- 2549
- Human Swiss Prot No:
- Q13480
- Mouse Swiss Prot No:
- Q9QYY0
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
- Detection Method:
- Colorimetric
- Background:
- function:Probably involved in EGF and insulin receptor signaling.,PTM:Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.,similarity:Belongs to the GAB family.,similarity:Contains 1 PH domain.,subunit:Interacts with GRB2 and with other SH2-containing proteins. Interacts with phosphorylated LAT2.,
- Function:
- MAPKKK cascade, activation of MAPK activity, regulation of protein amino acid phosphorylation, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, response to oxidative stress, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, epidermal growth factor receptor signaling pathway, intracellular signaling cascade, protein kinase cascade, JNK cascade, activation of JUN kinase activity, cell proliferation, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, response to organic substance, regulation of protein kinase cascade, phosphorylation, regulation of phosphate metabolic process,regulation of cell migration, stress-activated protein kinase signaling pathway, regulation of protein modific
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