Total ATF-1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3026C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • ATF1
    • Human Gene Id:
    • 466
    • Human Swiss Prot No:
    • P18846
    • Mouse Swiss Prot No:
    • P81269
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) (Activating transcription factor 1) (Protein TREB36)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:A chromosomal aberration involving ATF1 is associated with angiomatoid fibrous histiocytoma (AFH) [MIM:612160]. Translocation t(12;16)(q13;p11.2) with FUS generates a chimeric ATF1/FUS protein.,disease:A chromosomal aberration involving ATF1 is associated with angiomatoid fibrous histiocytoma (AFH) [MIM:612160]. Translocation t(12;22)(q13;q12) with EWSR1 generates a chimeric ATF1/EWSR1 protein.,function:This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes.,similarity:Belongs to the bZIP family. ATF subfamily.,similarity:Contains 1 bZIP domain.,similarity:Contains 1 KID (kinase-inducible) domain.,subunit:Binds DNA as a dimer.,
    • Function:
    • transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
    • Subcellular Location:
    • Nucleus .