Phospho MYB (S12) Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA1304C
  • Applications:ELISA
  • Reactivity:Human;Mouse
    • Gene Name:
    • MYB
    • Human Gene Id:
    • 4602
    • Human Swiss Prot No:
    • P10242
    • Mouse Swiss Prot No:
    • P06876
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Transcriptional activator Myb (Proto-oncogene c-Myb)
    • Detection Method:
    • Colorimetric
    • Background:
    • domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
    • Function:
    • transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
    • Subcellular Location:
    • Nucleus .