Phospho IL-3Rβ (Y593) Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA1261C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • CSF2RB
    • Human Gene Id:
    • 1439
    • Human Swiss Prot No:
    • P32927
    • Mouse Swiss Prot No:
    • P26955
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Cytokine receptor common subunit beta (CDw131) (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
    • Detection Method:
    • Colorimetric
    • Background:
    • disease:Defects in CSF2RB are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease.,domain:The box 1 motif is required for JAK interaction and/or activation.,domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.,function:High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily.,similarity:Contains 2 fibronectin type-III domains.,subunit:Heterodimer of an alpha and a beta subunit. The beta subunit is common to the IL3, IL5 and GM-CSF receptors.,
    • Function:
    • respiratory gaseous exchange, cytokine-mediated signaling pathway,
    • Subcellular Location:
    • Membrane; Single-pass type I membrane protein.