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WDR62 rabbit pAb

货号：YT7579
应用：WB
种属：Human;Mouse

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靶点：
WDR62

基因名称：
WDR62 C19orf14

蛋白名称：
WDR62

Human Gene Id：
284403

Human Swiss Prot No：
O43379

Mouse Swiss Prot No：
Q3U3T8

免疫原：
Synthesized peptide derived from human WDR62 AA range: 984-1034

特异性：
This antibody detects endogenous levels of WDR62 at Human/Mouse

组成：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

来源：
Polyclonal, Rabbit,IgG

稀释：
WB 1：500-2000

纯化工艺：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度：
1 mg/ml

储存：
-15°C to -25°C/1 year(Do not lower than -25°C)

分子量：
167kD

背景：
This gene is proposed to play a role in cerebral cortical development. Mutations in this gene have been associated with microencephaly, cortical malformations, and mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011],

功能：
similarity:Contains 15 WD repeats.,

细胞定位：
Nucleus . Cytoplasm, cytoskeleton, spindle pole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis. Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles. .

组织表达：
Present in fetal brain, enriched within the ventricular and subventricular zone (at protein level). In the embryonic brain it is expressed in mitotic neural precursor cells.

TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways. Hepatobiliary & Pancreatic Diseases International Yong Wang WB Human hepatocellular cancer (HCC) tissues
货号：YT7579