- 靶点:
- PHLP2
- 简介:
- >>PI3K-Akt signaling pathway
- 基因名称:
- PHLPP2 KIAA0931 PHLPPL
- 蛋白名称:
- PHLP2
- Human Gene Id:
- 23035
- Human Swiss Prot No:
- Q6ZVD8
- Mouse Gene Id:
- 244650
- Mouse Swiss Prot No:
- Q8BXA7
- 免疫原:
- Synthesized peptide derived from human PHLP2 AA range: 381-431
- 特异性:
- This antibody detects endogenous levels of PHLP2 at Human/Mouse
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 分子量:
- 146kD
- 细胞定位:
- Cytoplasm. Membrane; Peripheral membrane protein. Nucleus. In colorectal cancer tissue, expression is concentrated in the cytoplasm and nucleus.
- 组织表达:
- In colorectal cancer tissue, expression is highest in the surface epithelium of normal colonic mucosa adjacent to the cancer tissue but is largely excluded from the crypt bases. Expression is lost or significantly decreased in 80% of tested tumors (at protein level).
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- Antibody-FAQs
- 产品图片
- Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).