• 靶点：
• CD138

• 简介：
• >>ECM-receptor interaction;>>Cell adhesion molecules;>>Malaria;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis

• 基因名称：
• SDC1

• 蛋白名称：
• Syndecan-1

• Human Gene Id：
• 6382

• Human Swiss Prot No：
• P18827

• Mouse Swiss Prot No：
• P18828

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human SDC1. AA range:191-240

• 特异性：
• CD138 Polyclonal Antibody detects endogenous levels of CD138 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• SDC1;SDC;Syndecan-1;SYND1;CD138

• 实测条带：
• 34kD

• 背景：
• The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008],

• 功能：
• function:Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Interacts with CDCP1.,

• 细胞定位：
• Membrane ; Single-pass type I membrane protein . Secreted . Secreted, extracellular exosome . Shedding of the ectodomain produces a soluble form. .

• 组织表达：
• Dermoid cancer,Fibroblast,Kidney,Mammary gland,Placenta,

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货号：YT5610

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