CD138 Polyclonal Antibody
- 货号:YT5610
- 应用:WB;IHC;IF;ELISA
- 种属:Human;Rat;Mouse;
- 简介:
- >>ECM-receptor interaction;>>Cell adhesion molecules;>>Malaria;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis
- 免疫原:
- The antiserum was produced against synthesized peptide derived from the Internal region of human SDC1. AA range:191-240
- 特异性:
- CD138 Polyclonal Antibody detects endogenous levels of CD138 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- SDC1;SDC;Syndecan-1;SYND1;CD138
- 背景:
- The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008],
- 功能:
- function:Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Interacts with CDCP1.,
- 细胞定位:
- Membrane ; Single-pass type I membrane protein . Secreted . Secreted, extracellular exosome . Shedding of the ectodomain produces a soluble form. .
- 组织表达:
- Dermoid cancer,Fibroblast,Kidney,Mammary gland,Placenta,
![](/uploadfiles/PIC/yt5610-wb.jpg)
- Western Blot analysis of 293 cells using CD138 Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
![](/uploadfiles/PIC/yt5610ihchuman-tonsils.jpg)
- Immunohistochemical analysis of paraffin-embedded human-tonsils, antibody was diluted at 1:100