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Ox40 Polyclonal Antibody

货号：YT5607
应用：WB;ELISA
种属：Human;Rat;Mouse;

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靶点：
Ox40

简介：
>>Cytokine-cytokine receptor interaction

基因名称：
TNFRSF4

蛋白名称：
Tumor necrosis factor receptor superfamily member 4

Human Gene Id：
7293

Human Swiss Prot No：
P43489

Mouse Swiss Prot No：
P47741

免疫原：
The antiserum was produced against synthesized peptide derived from the Internal region of human TNFRSF4. AA range:131-180

特异性：
Ox40 Polyclonal Antibody detects endogenous levels of Ox40 protein.

组成：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

来源：
Polyclonal, Rabbit,IgG

稀释：
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

纯化工艺：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度：
1 mg/ml

储存：
-15°C to -25°C/1 year(Do not lower than -25°C)

其他名称：
TNFRSF4;TXGP1L;Tumor necrosis factor receptor superfamily member 4;ACT35 antigen;OX40L receptor;TAX transcriptionally-activated glycoprotein 1 receptor;CD134

实测条带：
30kD

背景：
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008],

功能：
function:Receptor for TNFSF4/OX40L/GP34.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5.,

细胞定位：
Membrane; Single-pass type I membrane protein.

组织表达：
Brain,

TuBG1 promotes hepatocellular carcinoma via ATR/P53-apoptosis and cycling pathways. Hepatobiliary & Pancreatic Diseases International Yong Wang WB Human hepatocellular cancer (HCC) tissues
货号：YT5607