• 靶点：
• CD107a

• 简介：
• >>Autophagy - animal;>>Lysosome;>>Phagosome;>>Tuberculosis

• 基因名称：
• LAMP1

• 蛋白名称：
• Lysosome-associated membrane glycoprotein 1

• Human Gene Id：
• 3916

• Human Swiss Prot No：
• P11279

• Mouse Swiss Prot No：
• P11438

• Rat Gene Id：
• 25328

• Rat Swiss Prot No：
• P14562

• 免疫原：
• The antiserum was produced against synthesized peptide derived from the Internal region of human LAMP1. AA range:211-260

• 特异性：
• CD107a Polyclonal Antibody detects endogenous levels of CD107a protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• LAMP1;Lysosome-associated membrane glycoprotein 1;LAMP-1;Lysosome-associated membrane protein 1;CD107 antigen-like family member A;CD107a

• 实测条带：
• 120kD

• 背景：
• The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008],

• 功能：
• function:Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane.,

• 细胞定位：
• Cell membrane ; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Late endosome membrane ; Single-pass type I membrane protein . Cytolytic granule membrane ; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). .

• 组织表达：
• Brain,Liver,Pancreas,Placenta,Plasma,Testis,

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