- 靶点:
- Calbindin D28K
- 简介:
- >>Endocrine and other factor-regulated calcium reabsorption
- 基因名称:
- CALB1
- 蛋白名称:
- Calbindin
- Human Gene Id:
- 793
- Human Swiss Prot No:
- P05937
- Mouse Gene Id:
- 12307
- Mouse Swiss Prot No:
- P12658
- Rat Gene Id:
- 83839
- Rat Swiss Prot No:
- P07171
- 免疫原:
- The antiserum was produced against synthesized peptide derived from the C-terminal region of human CALB1. AA range:191-240
- 特异性:
- Calbindin D28K Polyclonal Antibody detects endogenous levels of Calbindin D28K protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- CALB1;CAB27;Calbindin;Calbindin D28;D-28K;Vitamin D-dependent calcium-binding protein, avian-type
- 实测条带:
- 30kD
- 背景:
- The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015],
- 功能:
- domain:This protein has four functional calcium-binding sites; potential sites II and VI have lost affinity for calcium.,function:Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.,online information:Calbindin entry,similarity:Belongs to the calbindin family.,similarity:Contains 5 EF-hand domains.,subunit:Interacts with RANBP9.,
- 细胞定位:
- nucleus,cytosol,axon,dendrite,neuronal cell body,terminal bouton,synapse,extracellular exosome,
- 组织表达:
- Brain,Cerebellum,Kidney,Lung,Substantia nigra,
High albumen height by expression of GALNT9 and thin eggshell by decreased Ca2+ transportation caused high hatchability in Huainan partridge chicken POULTRY SCIENCE Wanli Yang WB chicken 1:1000 uterus tissue
货号:YT5209
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of K562 cells using Calbindin D28K Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Immunohistochemical analysis of paraffin-embedded rat-brain, antibody was diluted at 1:100