TRAAK Polyclonal Antibody
- 货号：YT4714
- 应用：WB;ELISA
- 种属：Human;Mouse
- 蛋白名称：
- Potassium channel subfamily K member 4
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human KCNK4. AA range:332-381
- 特异性：
- TRAAK Polyclonal Antibody detects endogenous levels of TRAAK protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- KCNK4;TRAAK;Potassium channel subfamily K member 4;TWIK-related arachidonic acid-stimulated potassium channel protein;TRAAK;Two pore potassium channel KT4.1;Two pore K(+) channel KT4.1
- 背景：
- This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015],
- 功能：
- function:Voltage insensitive, instantaneous, outwardly rectifying potassium channel. Outward rectification is reversed at high external K(+) concentrations.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein .
- 组织表达：
- Brain,Frontal cortex,
- Western Blot analysis of various cells using TRAAK Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
- Western blot analysis of lysates from HT-29 cells, using KCNK4 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HUVECcells using KCNK4 antibody.
