- 靶点：
- Syndecan-2
- 简介：
- >>Cell adhesion molecules;>>Malaria;>>Proteoglycans in cancer;>>Fluid shear stress and atherosclerosis
- 基因名称：
- SDC2
- 蛋白名称：
- Syndecan-2
- Human Gene Id：
- 6383
- Human Swiss Prot No：
- P34741
- Mouse Swiss Prot No：
- P43407
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human SDC2. AA range:81-130
- 特异性：
- Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SDC2;HSPG1;Syndecan-2;SYND2;Fibroglycan;Heparan sulfate proteoglycan core protein;HSPG;CD antigen CD362
- 实测条带：
- 22kD
- 背景：
- The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008],
- 功能：
- function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,
- 细胞定位：
- Membrane; Single-pass type I membrane protein.
- 组织表达：
- Brain,Embryo,Lung fibroblast,Muscle,Testis,
MiR-20a-5p represses the multi-drug resistance of osteosarcoma by targeting the SDC2 gene. Cancer Cell International Cancer Cell Int. 2017 Dec;17(1):1-11 WB Human SJSA-1 cell,G-292 cell
货号：YT4490
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- Antibody-FAQs
- 产品图片
- Zhao, Fangfang, et al. "MiR-20a-5p represses the multi-drug resistance of osteosarcoma by targeting the SDC2 gene." Cancer cell international 17.1 (2017): 100.
- Western blot analysis of SDC2 Antibody. The lane on the right is blocked with the SDC2 peptide.
- Western blot analysis of the lysates from RAW264.7cells using SDC2 antibody.
