Sox-8/9/17/18 Polyclonal Antibody
- 货号：YT4370
- 应用：WB;IHC;IF;ELISA
- 种属：Human;Mouse;Monkey
- 靶点：
- Sox-8/9/17/18
- 基因名称：
- SOX8/9/17/18
- 蛋白名称：
- Transcription factor SOX-8/9/17/18
- Human Gene Id：
- 30812/6662/64321/54345
- Human Swiss Prot No：
- P57073/P48436/Q9H6I2/P35713
- Mouse Gene Id：
- 20681/20682/20671/20672
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human SOX8/9/17/18. AA range:116-165
- 特异性：
- Sox-8/9/17/18 Polyclonal Antibody detects endogenous levels of Sox-8/9/17/18 protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- SOX8;Transcription factor SOX-8;SOX9;Transcription factor SOX-9;SOX17;Transcription factor SOX-17;SOX18;Transcription factor SOX-18
- 实测条带：
- 47kD
- 背景：
- SRY-box 8(SOX8) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome). [provided by RefSeq, Jul 2008],
- 功能：
- function:May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.,similarity:Contains 1 HMG box DNA-binding domain.,
- 细胞定位：
- Nucleus .
- 组织表达：
- Brain,Spleen,
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of various cells using Sox-8/9/17/18 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using SOX8/9/17/18 Antibody. The picture on the right is blocked with the synthesized peptide.
- Western blot analysis of lysates from COS7 cells, treated with serum 10% 30', using SOX8/9/17/18 Antibody. The lane on the right is blocked with the synthesized peptide.
- Western blot analysis of the lysates from HeLa cells using SOX8/9/17/18 antibody.
