- 靶点:
- S-100A10
- 简介:
- >>Salmonella infection
- 基因名称:
- S100A10
- 蛋白名称:
- Protein S100-A10
- Human Gene Id:
- 6281
- Human Swiss Prot No:
- P60903
- Mouse Gene Id:
- 20194
- Mouse Swiss Prot No:
- P08207
- Rat Gene Id:
- 81778
- Rat Swiss Prot No:
- P05943
- 免疫原:
- The antiserum was produced against synthesized peptide derived from human S-100A10. AA range:3-52
- 特异性:
- S-100A10 Polyclonal Antibody detects endogenous levels of S-100A10 protein.
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- S100A10;ANX2LG;CAL1L;CLP11;Protein S100-A10;Calpactin I light chain;Calpactin-1 light chain;Cellular ligand of annexin II;S100 calcium-binding protein A10;p10 protein;p11
- 实测条带:
- 11kD
- 背景:
- The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008],
- 功能:
- function:Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.,miscellaneous:Does not appear to bind calcium. Contains 2 ancestral calcium site related to EF-hand domains that have lost their ability to bind calcium.,similarity:Belongs to the S-100 family.,subunit:Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A.,
- 细胞定位:
- integral component of membrane,extrinsic component of plasma membrane,membrane raft,extracellular exosome,
- 组织表达:
- Brain,Keratinocyte,
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- Antibody-FAQs
- 产品图片
- Western Blot analysis of various cells using S-100A10 Polyclonal Antibody
- Immunohistochemistry analysis of S-100A10 antibody in paraffin-embedded human lung carcinoma tissue.
- Western blot analysis of lysate from COLO cells, using S-100A10 antibody.