Rho GDIα Polyclonal Antibody
- 货号：YT4081
- 应用：IHC;IF;ELISA
- 种属：Human;Mouse;Rat
- 简介：
- >>Neurotrophin signaling pathway;>>Vasopressin-regulated water reabsorption
- 蛋白名称：
- Rho GDP-dissociation inhibitor 1
- 免疫原：
- The antiserum was produced against synthesized peptide derived from human ARHGDIA. AA range:140-189
- 特异性：
- Rho GDIα Polyclonal Antibody detects endogenous levels of Rho GDIα protein.
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称：
- ARHGDIA;GDIA1;Rho GDP-dissociation inhibitor 1;Rho GDI 1;Rho-GDI alpha
- 背景：
- This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
- 功能：
- function:Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.,similarity:Belongs to the Rho GDI family.,subunit:Monomer.,
- 组织表达：
- Brain,Cajal-Retzius cell,Colon,Epithelium,Fetal brain cortex,Lung,M
- Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue, using ARHGDIA Antibody. The picture on the right is blocked with the synthesized peptide.
