• 靶点：
• QM

• 简介：
• >>Ribosome;>>Coronavirus disease - COVID-19

• 基因名称：
• RPL10

• 蛋白名称：
• 60S ribosomal protein L10

• Human Gene Id：
• 6134

• Human Swiss Prot No：
• P27635

• Mouse Gene Id：
• 110954

• Mouse Swiss Prot No：
• Q6ZWV3

• Rat Gene Id：
• 81764

• Rat Swiss Prot No：
• Q6PDV7

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human 60S Ribosomal Protein L10. AA range:1-50

• 特异性：
• QM Polyclonal Antibody detects endogenous levels of QM protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• RPL10;DXS648E;QM;60S ribosomal protein L10;Laminin receptor homolog;Protein QM;Tumor suppressor QM

• 实测条带：
• 25kD

• 背景：
• This gene encodes a ribosomal protein that is a component of the 60S ribosome subunit. The related protein in chicken can bind to c-Jun and can repress c-Jun-mediated transcriptional activation. Some studies have detected an association between variation in this gene and autism spectrum disorders, though others do not detect this relationship. There are multiple pseudogenes of this gene dispersed throughout the genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],

• 功能：
• developmental stage:Down-regulated during adipocyte, kidney, and heart differentiation.,disease:Defects in RPL10 may be the cause of susceptibility to X-linked autism [MIM:209850]. Autism is a pervasive developmental disorder (PDD), prototypically characterized by impairments in reciprocal social interaction and communication, restricted and stereotyped patterns of interests and activities, and the presence of developmental abnormalities by 3 years of age.,similarity:Belongs to the ribosomal protein L10e family.,

• 细胞定位：
• endoplasmic reticulum,cytosol,ribosome,membrane,cytosolic large ribosomal subunit,

• 组织表达：
• Brain,Human lung,Mammary cancer,Mammary gland,Ovarian carcinoma,Pancreatic cancer,P

Profiling of Host Cell Response to Successive Canine Parvovirus Infection Based on Kinetic Proteomic Change Identification. Scientific Reports 2016 Jul 13 WB Cat F81 cell
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