• 靶点：
• Peripherin

• 简介：
• >>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases

• 基因名称：
• PRPH

• 蛋白名称：
• Peripherin

• Human Gene Id：
• 5630

• Human Swiss Prot No：
• P41219

• Mouse Swiss Prot No：
• P15331

• Rat Swiss Prot No：
• P21807

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human Peripherin. AA range:421-470

• 特异性：
• PRPH Polyclonal Antibody detects endogenous levels of PRPH protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• PRPH;NEF4;PRPH1;Peripherin;Neurofilament 4

• 实测条带：
• 55kD

• 背景：
• This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008],

• 功能：
• function:Class-III neuronal intermediate filament protein.,online information:Peripherin entry,similarity:Belongs to the intermediate filament family.,

• 细胞定位：
• Cytoplasm, cytoskeleton . Cell projection, axon . Perikaryon .

• 组织表达：
• Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.

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