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GPR50 Polyclonal Antibody

货号：YT2024
应用：WB;IF;ELISA
种属：Human;Rat;Mouse;

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靶点：
GPR50

简介：
>>Neuroactive ligand-receptor interaction

基因名称：
GPR50

蛋白名称：
Melatonin-related receptor

Human Gene Id：
9248

Human Swiss Prot No：
Q13585

Mouse Swiss Prot No：
O88495

免疫原：
The antiserum was produced against synthesized peptide derived from human MTR1L. AA range:301-350

特异性：
GPR50 Polyclonal Antibody detects endogenous levels of GPR50 protein.

组成：
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

来源：
Polyclonal, Rabbit,IgG

稀释：
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

纯化工艺：
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

浓度：
1 mg/ml

储存：
-15°C to -25°C/1 year(Do not lower than -25°C)

其他名称：
GPR50;Melatonin-related receptor;G protein-coupled receptor 50;H9

实测条带：
68kD

背景：
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010],

功能：
function:Does not bind melatonin.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Hypothalamus and pituitary.,

细胞定位：
Cell membrane; Multi-pass membrane protein.

组织表达：
Hypothalamus and pituitary.

Neuroprotective effect of acute melatonin treatment on hippocampal neurons against irradiation by inhibition of caspase‑3. Experimental and Therapeutic Medicine Exp Ther Med. 2016 Jun;11(6):2385-2390 IHC Rat hippocampi
货号：YT2024