• 靶点：
• FOSL2

• 简介：
• >>Osteoclast differentiation

• 基因名称：
• FOSL2

• 蛋白名称：
• Fos-related antigen 2

• Human Gene Id：
• 2355

• Human Swiss Prot No：
• P15408

• Mouse Gene Id：
• 14284

• Mouse Swiss Prot No：
• P47930

• Rat Gene Id：
• 25446

• Rat Swiss Prot No：
• P51145

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human Fra-2. AA range:271-320

• 特异性：
• FOSL2 Polyclonal Antibody detects endogenous levels of FOSL2 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• FOSL2;FRA2;Fos-related antigen 2;FRA-2

• 实测条带：
• 43kD

• 背景：
• The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. [provided by RefSeq, Jul 2014],

• 功能：
• similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Fos subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Endothelial cell,Epithelium,Lung,

Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28. Chuanxin Wang Mouse 1:50 pancreas tissue
货号：YT1739

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