• 靶点：
• Cytochrome c1

• 简介：
• >>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy

• 基因名称：
• CYC1

• 蛋白名称：
• Cytochrome c1 heme protein mitochondrial

• Human Gene Id：
• 1537

• Human Swiss Prot No：
• P08574

• Mouse Gene Id：
• 66445

• Mouse Swiss Prot No：
• Q9D0M3

• 免疫原：
• The antiserum was produced against synthesized peptide derived from human CYC1. AA range:132-181

• 特异性：
• Cytochrome c1 Polyclonal Antibody detects endogenous levels of Cytochrome c1 protein.

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000; IF ICC 1:100-500;ELISA 1:5000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• CYC1;Cytochrome c1; heme protein, mitochondrial;Complex III subunit 4;Complex III subunit IV;Cytochrome b-c1 complex subunit 4;Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit;Cytochrome c-1

• 实测条带：
• 35kD

• 背景：
• This gene encodes a subunit of the cytochrome bc1 complex, which plays an important role in the mitochondrial respiratory chain by transferring electrons from the Rieske iron-sulfur protein to cytochrome c. Mutations in this gene may cause mitochondrial complex III deficiency, nuclear type 6. [provided by RefSeq, Dec 2013],

• 功能：
• function:This is the heme-containing component of the cytochrome b-c1 complex, which accepts electrons from Rieske protein and transfers electrons to cytochrome c in the mitochondrial respiratory chain.,PTM:Binds 1 heme group per subunit.,similarity:Belongs to the cytochrome c family.,subunit:The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).,

• 细胞定位：
• Mitochondrion inner membrane ; Single-pass membrane protein .

• 组织表达：
• Brain,Kidney,Lung,Skin,

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