Calpain 12 Polyclonal Antibody

    • 货号:YT0616
    • 应用:WB;ELISA
    • 种属:Human;Mouse
      • 靶点:
      • Calpain 12
      • 基因名称:
      • CAPN12
      • 蛋白名称:
      • Calpain-12
      • Human Swiss Prot No:
      • Q6ZSI9
      • Mouse Swiss Prot No:
      • Q9ER56
      • 免疫原:
      • The antiserum was produced against synthesized peptide derived from human CAPN12. AA range:221-270
      • 特异性:
      • Calpain 12 Polyclonal Antibody detects endogenous levels of Calpain 12 protein.
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • CAPN12;Calpain-12;Calcium-activated neutral proteinase 12;CANP 12
      • 实测条带:
      • 80kD
      • 背景:
      • The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012],
      • 功能:
      • catalytic activity:Broad endopeptidase specificity.,function:Calcium-regulated non-lysosomal thiol-protease.,similarity:Belongs to the peptidase C2 family.,similarity:Contains 1 calpain catalytic domain.,similarity:Contains 1 EF-hand domain.,
      • 细胞定位:
      • intracellular,cytoplasm,
      • 组织表达:
      • Thalamus,

      3, 3'-Diindolylmethane induces gastric cancer cells death via STIM1 mediated store-operated calcium entry." International Journal of Biological Sciences 17.5 (2021): 1217.
      货号:YT0616

      • 产品图片
      • Western Blot analysis of various cells using Calpain 12 Polyclonal Antibody
      • Western Blot analysis of 293 cells using Calpain 12 Polyclonal Antibody
      • Western blot analysis of the lysates from K562 cells using CAPN12 antibody.