Iba1 (PT0288R) PT® Rabbit mAb

    • 货号:YM8165
    • 应用:WB;IHC;IF;IP;ELISA
    • 种属:Human; Mouse; Rat;
      • 蛋白名称:
      • AIF1 G1 IBA1
      • 序列:
      • Allograft inflammatory factor 1 (AIF-1) (Ionized calcium-binding adapter molecule 1) (Protein G1)
      • Human Gene Id:
      • 199
      • Human Swiss Prot No:
      • P55008
      • Mouse Swiss Prot No:
      • O70200
      • 特异性:
      • endogenous
      • 组成:
      • PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
      • 来源:
      • Monoclonal, rabbit, IgG, Kappa
      • 稀释:
      • IHC 1:2000-1:4000,WB 1:1000-1:5000,IF 1:200-1:1000,ELISA 1:5000-1:20000,IP 1:50-1:200,
      • 纯化工艺:
      • Protein A
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 其他名称:
      • AIF 1;AIF-1;Aif1;AIF1 protein;AIF1_HUMAN;Allograft inflammatory factor 1;Allograft inflammatory factor 1 splice variant G;allograft inflammatory factor-1 splice variant Hara-1;balloon angioplasty responsive transcription;BART 1;G1;G1 putative splice variant of allograft inflamatory factor 1;IBA 1;IBA1;interferon gamma responsive transcript;Interferon responsive transcript 1;interferon responsive transcript factor 1;Ionized calcium binding adapter molecule 1;Ionized calcium-binding adapter molecule 1;ionized calcium-binding adapter molecule;IRT 1;IRT1;Microglia response factor;MRF1;Protein g1;
      • 分子量:
      • 16kD
      • 实测条带:
      • 16kD
      • 背景:
      • This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016],
      • 功能:
      • function:May play a role in macrophage activation and function.,PTM:Phosphorylated on serine residues.,similarity:Contains 2 EF-hand domains.,
      • 细胞定位:
      • Cytoplasm
      • 组织表达:
      • Detected in T-lymphocytes and peripheral blood mononuclear cells.

      The toxic influence of dibromoacetic acid on the hippocampus and pre-frontal cortex of rat: involvement of neuroinflammation response and oxidative stress. METABOLIC BRAIN DISEASE Metab Brain Dis. 2017 Dec;32(6):2009-2019 WB Rat 1:800 Pre-frontal cortical,hippocampal tissues
      货号:YM8165

      A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia JOURNAL OF ETHNOPHARMACOLOGY Kai-Ting Ma IF Rat 1:300 brain tissue
      货号:YM8165

      • 产品图片
      • Human tonsil was stained with anti-Iba1 (PT0288R) rabbit antibody
      • Mouse liver was stained with anti-Iba1 (PT0288R) rabbit antibody
      • Rat liver was stained with anti-Iba1 (PT0288R) rabbit antibody
      • Various whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-Iba1 (PT0288R) antibody. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody. Lane 1: Rat brain Lane 2: RAW264.7 Lane 3: THP-1 Predicted band size: 16kDa Observed band size: 16kDa
      • Human liver was stained with anti-Iba1 (PT0288R) rabbit antibody