Total CYP4F2 Cell-Based Colorimetric ELISA Kit
- 货号：KA3901C
- 应用：ELISA
- 种属：Human
- 其他名称：
- Leukotriene-B(4) omega-hydroxylase 1 (EC 1.14.13.30) (CYPIVF2) (Cytochrome P450 4F2) (Cytochrome P450-LTB-omega) (Leukotriene-B(4) 20-monooxygenase 1)
- 背景：
- catalytic activity:(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + O(2) = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP(+) + H(2)O.,cofactor:Heme group.,function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.,similarity:Belongs to the cytochrome P450 family.,tissue specificity:Liver.,
- 功能：
- fatty acid metabolic process, icosanoid metabolic process, leukotriene metabolic process, unsaturated fatty acid metabolic process, cellular alkene metabolic process, oxidation reduction,
- 细胞定位：
- Microsome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein .
- 组织表达：
- Liver. Also present in kidney: specifically expressed in the S2 and S3 segments of proximal tubules in cortex and outer medulla (PubMed:10660572).
