• 基因名称：
• WTAP

• Human Gene Id：
• 9589

• Human Swiss Prot No：
• Q15007

• Mouse Swiss Prot No：
• Q9ER69

• 储存：
• 2-8°C/6 months

• 其他名称：
• Pre-mRNA-splicing regulator WTAP (Female-lethal(2)D homolog) (hFL(2)D) (WT1-associated protein) (Wilms tumor 1-associating protein)

• 检测方法：
• Colorimetric

• 背景：
• function:Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. May be involved in mRNA splicing regulation.,induction:In smooth muscle cells, up-regulated after serum withdrawal, when cells become mature and non proliferative.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the fl(2)d family.,subunit:Interacts with WT1.,tissue specificity:Ubiquitously expressed.,

• 功能：
• RNA processing, mRNA processing, cell cycle, RNA splicing, mRNA metabolic process,

• 细胞定位：
• Nucleus speckle . Nucleus, nucleoplasm . Cytoplasm . Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus. .

• 组织表达：
• Ubiquitously expressed.

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