Total TLE4 Cell-Based Colorimetric ELISA Kit
- 货号：KA3680C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 其他名称：
- Transducin-like enhancer protein 4
- 背景：
- caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation.,function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.,similarity:Belongs to the WD repeat Groucho/TLE family.,similarity:Contains 7 WD repeats.,subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2.,tissue specificity:In all tissues examined, mostly in brain, and muscle.,
- 功能：
- transcription, cell surface receptor linked signal transduction, Wnt receptor signaling pathway, regulation of transcription,
- 组织表达：
- In all tissues examined, mostly in brain, and muscle.
