• 基因名称：
• ZFP36L2

• Human Gene Id：
• 678

• Human Swiss Prot No：
• P47974

• Mouse Swiss Prot No：
• P23949

• 储存：
• 2-8°C/6 months

• 其他名称：
• Zinc finger protein 36, C3H1 type-like 2 (ZFP36-like 2) (Butyrate response factor 2) (EGF-response factor 2) (ERF-2) (Protein TIS11D)

• 检测方法：
• Colorimetric

• 背景：
• function:Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation.,similarity:Contains 2 C3H1-type zinc fingers.,

• 功能：
• nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, nuclear-transcribed mRNA catabolic process, RNA catabolic process, mRNA catabolic process, cell proliferation, macromolecule catabolic process,posttranscriptional regulation of gene expression, mRNA metabolic process, regulation of RNA stability, regulation of mRNA stability, cellular macromolecule catabolic process, regulation of RNA metabolic process,

• 细胞定位：
• Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. .

• 组织表达：
• Expressed mainly in the basal epidermal layer, weakly in the suprabasal epidermal layers (PubMed:27182009). Expressed in epidermal keratinocytes (at protein level) (PubMed:27182009).

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