Total PKA Iβ reg Cell-Based Colorimetric ELISA Kit
- 货号:KA3585C
- 应用:ELISA
- 种属:Human;Mouse;Rat
- 基因名称:
- PRKAR1B
- Human Gene Id:
- 5575
- Human Swiss Prot No:
- P31321
- Mouse Swiss Prot No:
- P12849
- Rat Swiss Prot No:
- P81377
- 储存:
- 2-8°C/6 months
- 其他名称:
- cAMP-dependent protein kinase type I-beta regulatory subunit
- 检测方法:
- Colorimetric
- 背景:
- PTM:The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity.,similarity:Belongs to the cAMP-dependent kinase regulatory chain family.,similarity:Contains 2 cyclic nucleotide-binding domains.,subunit:The inactive form of the enzyme is composed of two regulatory chains and two catalytic chains. Activation by cAMP produces two active catalytic monomers and a regulatory dimer that binds four cAMP molecules.,tissue specificity:Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.,
- 功能:
- regulation of protein amino acid phosphorylation, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, intracellular signaling cascade, behavior, learning or memory, response to endogenous stimulus, response to hormone stimulus, hormone-mediated signaling, response to organic substance,phosphorylation, regulation of phosphate metabolic process, regulation of protein modification process, activation of protein kinase activity, regulation of cellular protein metabolic process, cellular response to hormone stimulus, positive regulation of kinase activity, activation of protein kinase A activity, regulation of phosphorylation, positive regulation of catalytic activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, neurological system proc
- 细胞定位:
- Cell membrane .
- 组织表达:
- Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
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