Total Glucosidase IIβ Cell-Based Colorimetric ELISA Kit

  • 货号:KA3542C
  • 应用:ELISA
  • 种属:Human;Mouse
    • 基因名称:
    • PRKCSH
    • Human Gene Id:
    • 5589
    • Human Swiss Prot No:
    • P14314
    • Mouse Swiss Prot No:
    • O08795
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Glucosidase 2 subunit beta (80K-H protein) (Glucosidase II subunit beta) (Protein kinase C substrate 60.1 kDa protein heavy chain) (PKCSH)
    • 检测方法:
    • Colorimetric
    • 背景:
    • disease:Defects in PRKCSH are a cause of polycystic liver disease (PCLD) [MIM:174050]. PCLD is an autosomal dominant disorder and is characterized by the presence of multiple liver cysts of biliary epithelial origin. PCLD is a distinct clinical and genetic entity that can occur independently from autosomal dominant polycystic kidney disease (ADPKD) [MIM:173900], which in a considerable but uncertain proportion of cases is associated with hepatic cysts.,function:Regulatory subunit of glucosidase II.,pathway:Glycan metabolism; N-glycan metabolism.,similarity:Contains 1 PRKCSH domain.,similarity:Contains 2 EF-hand domains.,subunit:Heterodimer of a catalytic alpha subunit (GANAB) and a beta subunit (PRKCSH). Binds glycosylated PTPRC.,
    • 功能:
    • intracellular signaling cascade, protein kinase cascade,
    • 细胞定位:
    • Endoplasmic reticulum .