Total DNA pol α Cell-Based Colorimetric ELISA Kit

  • 货号:KA3532C
  • 应用:ELISA
  • 种属:Human
    • 基因名称:
    • POLA1
    • Human Gene Id:
    • 5422
    • Human Swiss Prot No:
    • P09884
    • Mouse Swiss Prot No:
    • P33609
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • DNA polymerase alpha catalytic subunit (EC 2.7.7.7) (DNA polymerase alpha catalytic subunit p180)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,function:Polymerase alpha in a complex with DNA primase is a replicative polymerase.,miscellaneous:In eukaryotes there are five DNA polymerases: alpha, beta, gamma, delta, and epsilon which are responsible for different reactions of DNA synthesis.,PTM:A 165 kDa form is probably produced by proteolytic cleavage at Lys-124.,similarity:Belongs to the DNA polymerase type-B family.,subunit:Interacts with SV40 Large T antigen; this interaction allows viral DNA replication.,
    • 功能:
    • S phase of mitotic cell cycle, mitotic cell cycle, non-recombinational repair, DNA synthesis during DNA repair, DNA metabolic process, DNA replication, DNA-dependent DNA replication, DNA replication initiation, DNA strand elongation during DNA replication, leading strand elongation, lagging strand elongation, DNA repair, double-strand break repair,double-strand break repair via nonhomologous end joining, response to DNA damage stimulus, cell cycle, cell proliferation, cell cycle process, cell cycle phase, DNA strand elongation, cellular response to stress, S phase,interphase, interphase of mitotic cell cycle,
    • 细胞定位:
    • Nucleus . Cytoplasm, cytosol . In the cytosol, colocalizes with RNA:DNA hybrids with a speckled pattern. .