Total MMP-10 Cell-Based Colorimetric ELISA Kit

  • 货号:KA3323C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • MMP10
    • Human Gene Id:
    • 4319
    • Human Swiss Prot No:
    • P09238
    • Mouse Swiss Prot No:
    • O55123
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Stromelysin-2 (SL-2) (EC 3.4.24.22) (Matrix metalloproteinase-10) (MMP-10) (Transin-2)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:Similar to stromelysin 1, but action on collagen types III, IV and V is weak.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
    • 功能:
    • proteolysis, collagen catabolic process, collagen metabolic process, multicellular organismal metabolic process,multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
    • 细胞定位:
    • Secreted, extracellular space, extracellular matrix .