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Human MMP-10 ELISA Kit
- 货号:KE1171
- 应用:ELISA
- 种属:Human
- 特异性:
- Sample Type for Cell Culture Supernates, Cell lysates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma
- 其他名称:
- MMP10;STMY2;Stromelysin-2;SL-2;Matrix metalloproteinase-10;MMP-10;Transin-2
- 背景:
- catalytic activity:Similar to stromelysin 1, but action on collagen types III, IV and V is weak.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Calcium.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Can degrade fibronectin, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,
- 功能:
- proteolysis, collagen catabolic process, collagen metabolic process, multicellular organismal metabolic process,multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
- 细胞定位:
- Secreted, extracellular space, extracellular matrix .
- The Human Total MMP-10 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Total MMP-10 proteins within the range of 32-2000 pg/ml.