• 基因名称：
• FLI1

• Human Gene Id：
• 2313

• Human Swiss Prot No：
• Q01543

• Mouse Swiss Prot No：
• P26323

• 储存：
• 2-8°C/6 months

• 其他名称：
• Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) (Transcription factor ERGB)

• 检测方法：
• Colorimetric

• 背景：
• disease:A chromosomal aberration involving FLI1 is a cause of Ewing sarcoma [MIM:133450]. Translocation t(11;22)(q24;q12) with EWS.,function:Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.,miscellaneous:Located on a fragment of chromosome 11 flanked on the centromeric side by the acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation breakpoint and on the telomeric side by the Ewing- and neuroepithelioma-associated t(11;22) (q24;q12) breakpoint.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,similarity:Contains 1 PNT (pointed) domain.,subunit:Can form homodimers or heterodimers with ETV6/TEL1.,

• 功能：
• circulatory system process, transcription, regulation of transcription, DNA-dependent, hemostasis, blood circulation,regulation of transcription, regulation of body fluid levels, regulation of RNA metabolic process,

• 细胞定位：
• Nucleus .

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