Total DNA pol β Cell-Based Colorimetric ELISA Kit

  • 货号：KA3243C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • POLB
    • Human Gene Id：
    • 5423
    • Human Swiss Prot No：
    • P06746
    • Mouse Swiss Prot No：
    • Q8K409
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • DNA polymerase beta (EC 2.7.7.7) (EC 4.2.99.-)
    • 检测方法：
    • Colorimetric
    • 背景：
    • catalytic activity:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).,cofactor:Binds 2 magnesium ions per subunit.,domain:Residues 239-252 form a flexible loop which appears to affect the polymerase fidelity.,function:Repair polymerase. Conducts "gap-filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.,PTM:Methylation by PRMT6 stimulates the polymerase activity by enhancing DNA binding and processivity.,similarity:Belongs to the DNA polymerase type-X family.,subunit:Monomer.,
    • 功能：
    • DNA metabolic process, DNA replication, DNA-dependent DNA replication, DNA repair, base-excision repair, pyrimidine dimer repair, anti-apoptosis, response to DNA damage stimulus, cell death, regulation of cell death, death, cellular response to stress, regulation of apoptosis, negative regulation of apoptosis, regulation of programmed cell death,negative regulation of programmed cell death, negative regulation of cell death,
    • 细胞定位：
    • Nucleus. Cytoplasm. Cytoplasmic in normal conditions. Translocates to the nucleus following DNA damage.

    相关报价

    • 货号：
    • KA3243C
    • 规格：
    • 96 / well
    • 价格：
    • ¥3300
    • 货期：
    • 预计发货时间为
      2024-08-03
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