Total Claudin-4 Cell-Based Colorimetric ELISA Kit

  • 货号:KA3215C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • CLDN4
    • Human Gene Id:
    • 1364
    • Human Swiss Prot No:
    • O14493
    • Mouse Swiss Prot No:
    • O35054
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (Williams-Beuren syndrome chromosomal region 8 protein)
    • 检测方法:
    • Colorimetric
    • 背景:
    • disease:Haploinsufficiency of CLDN4 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space.,similarity:Belongs to the claudin family.,subunit:Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
    • 功能:
    • cell adhesion, pathogenesis, cell-cell adhesion, calcium-independent cell-cell adhesion, biological adhesion,
    • 细胞定位:
    • Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .