Total Claudin-4 Cell-Based Colorimetric ELISA Kit
- 货号:KA3215C
- 应用:ELISA
- 种属:Human;Mouse;Rat
- 基因名称:
- CLDN4
- Human Gene Id:
- 1364
- Human Swiss Prot No:
- O14493
- Mouse Swiss Prot No:
- O35054
- 储存:
- 2-8°C/6 months
- 其他名称:
- Claudin-4 (Clostridium perfringens enterotoxin receptor) (CPE-R) (CPE-receptor) (Williams-Beuren syndrome chromosomal region 8 protein)
- 检测方法:
- Colorimetric
- 背景:
- disease:Haploinsufficiency of CLDN4 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space.,similarity:Belongs to the claudin family.,subunit:Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
- 功能:
- cell adhesion, pathogenesis, cell-cell adhesion, calcium-independent cell-cell adhesion, biological adhesion,
- 细胞定位:
- Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . CLDN4 is required for tight junction localization in the kidney. .
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