CD34 (PN0491) Nb-FC recombinant antibody
- Catalog No.:YA0321
- Applications:FCM;ELISA
- Reactivity:Human
- Target:
- CD34
- Gene Name:
- CD34
- Protein Name:
- Hematopoietic progenitor cell antigen CD34 (CD antigen CD34)
- Human Gene Id:
- 947
- Human Swiss Prot No:
- P28906
- Immunogen:
- Purified recombinant Human CD34
- Specificity:
- This recombinant monoclonal antibody can detects endogenous levels of CD34 protein.
- Formulation:
- Phosphate-buffered solution
- Source:
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- Dilution:
- ELISA 1:5000-100000;FCM 1-2μg/Test
- Purification:
- Recombinant Expression and Affinity purified
- Concentration:
- Please check the information on the tube
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name:
- CD34 antibody;CD34 antigen antibody;CD34 molecule antibody;CD34_HUMAN antibody;Cluster designation 34 antibody;cluster of differentiation 34 antibody;Hematopoietic progenitor cell antigen CD34 antibody;HPCA1 antibody;Mucosialin antibody;OTTHUMP00000034733 antibody;OTTHUMP00000034734 antibody;CD34 nanobody;
- Background:
- The protein encoded byThis gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells.This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Aug 2011]
- Function:
- alternative products:Both isoforms are expressed on the cell surface. CD34-T/CD34-F ratio increases with cell differentiation,developmental stage:On early hematopoietic progenitor cells.,disease:Abnormal CD34 expression in leukemogenesis.,Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.,online information:CD34 entry,PTM:Highly glycosylated.,PTM:Phosphorylated on serine residues by PKC.,similarity:Belongs to the CD34 family.,tissue specificity:Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.,
- Subcellular Location:
- Membrane; Single-pass type I membrane protein.
- Expression:
- Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
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