CD27 (PN0504) Nb-FC recombinant antibody

  • Catalog No.:YA0224
  • Applications:FCM;ELISA
  • Reactivity:Human
    • Target:
    • CD27
    • Gene Name:
    • CD27 TNFRSF7
    • Protein Name:
    • CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
    • Human Gene Id:
    • 939
    • Human Swiss Prot No:
    • P26842
    • Immunogen:
    • Purified recombinant Human CD27
    • Specificity:
    • This recombinant monoclonal antibody can detects endogenous levels of CD27 protein.
    • Formulation:
    • Phosphate-buffered solution
    • Source:
    • Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
    • Dilution:
    • ELISA 1:5000-100000;FCM 1-2μg/Test
    • Purification:
    • Recombinant Expression and Affinity purified
    • Concentration:
    • Please check the information on the tube
    • Storage Stability:
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name:
    • CD 27 antibody;CD27 antibody;CD27 antigen antibody;CD27 molecule antibody;CD27_HUMAN antibody;CD27L receptor antibody;LPFS2 antibody;MGC20393 antibody;OTTHUMP00000238557 antibody;S152 antibody;T cell activation antigen CD27 antibody;T cell antivation antigen S152 antibody;T-cell activation antigen CD27 antibody;T14 antibody;TNFRSF 7 antibody;TNFRSF7 antibody;TNFSF7 antibody;Tp 55 antibody;Tp55 antibody;Tumor necrosis factor receptor superfamily member 7 antibody;CD27 nanobody;
    • Background:
    • CD27 molecule(CD27) Homo sapiens The protein encoded byThis gene is a member of the TNF-receptor superfamily.This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis.This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process ofThis receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind toThis receptor and is thought to play an important role in the apoptosis induced byThis receptor. [provided by RefSeq, Jul 2008]
    • Function:
    • Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
    • Subcellular Location:
    • Membrane; Single-pass type I membrane protein.
    • Expression:
    • Found in most T-lymphocytes.